Experts in Treating HLH

Hemophagocytic lymphohistiocytosis, or HLH, is a life-threatening condition. While HLH is rare, Cincinnati Children’s treats a large population of children with HLH. As part of one of the Top 5 pediatric hospitals in the U.S., the team at Cincinnati Children's is committed to changing the outcome for children with HLH.

Cincinnati Children’s HLH Center of Excellence

As the most experienced facility in North America for treating Hemophagocytic Lymphohistiocytosis (HLH), Cincinnati Children’s has assembled a team of researchers, physicians, philanthropists, and families who have faced an HLH diagnosis to create the HLH Center of Excellence.

A collaborative team of doctors, researchers, nurse managers and social workers led by one of the world’s leading authorities on HLH, Alexandra (Lisa) H. Filipovich, MD, supports the diagnosis, clinical care and treatment for HLH patients at Cincinnati Children’s.

The HLH Center treats patients from around the country, including adolescents and young adults. We will consult/evaluate patients of any age.

From diagnosis, to bone marrow transplant and long-term follow-up, the HLH Center of Excellence at Cincinnati Children’s provides physicians and families with a single resource for complete, family-centered care by the most respected HLH physicians.

Why Choose Cincinnati Children's?

World Leaders in HLH Treatment

Cincinnati Children's is the most experienced center in North America for the diagnosis and treatment of HLH. The HLH Center performs the largest number of bone marrow transplants for HLH each year in the US.

Diagnosis & Genetic Testing

Cincinnati Children's is the only medical center in North America offering the full range of genetic testing for HLH.

Leading the Field in Research

Cincinnati Children's HLH team includes six physician scientists focused on basic and translational research in HLH. Some of their ongoing innovative work includes the development of an HLH gene chip and novel protocols for initial treatment of HLH.

HLH Treatment at Cincinnati Children's - Maya's story

Mina Chamberlin tells the story of her daughter Maya's diagnosis of hemophagocytic lymphohistiocytosis (HLH) and moving to Cincinnati so she could receive treatment from Dr. Lisa Filipovich, a renowned expert on HLH. Maya underwent a life-saving bone marrow transplant at Cincinnati Children's. It's is Mina's hope that sharing Maya's story will encourage more people to register to be bone marrow donors.